| High-fat diet-induced obesity increases brain mitochondrial complex I and lipoxidation-derived protein damage |
2024 |
Berdun R; Obis E; Mota-Martorell N; Bassols A; Valent D; Serrano JCE; Martin-Gari M; Rodriguez-Palmero M; Moreno-Muñoz JA; Tibau J; Quintanilla R; Pamplona R; Portero-Otin M; Jove M. |
Article d'investigació |
| The shift in the fatty acid composition of the circulating lipidome in Alzheimer's disease |
2024 |
Dakterzada F; Jove M; Cantero JL; Mota-Martorell N; Pamplona R; Piñol-Ripoll G. |
Article d'investigació |
| Mitochondrial ROS production, oxidative stress and aging within and between species: evidences and recent advances on this aging effector. |
2023 |
Gomez J; Mota-Martorell N; Jove M; Pamplona R; Barja G. |
Article d'investigació |
| Ether lipid-mediated antioxidant defense in Alzheimer's disease. |
2023 |
Jove M; Mota-Martorell N; Obis E; Sol J; Martin-Gari M; Ferrer I; Portero-Otin M; Pamplona R |
Article d'investigació |
| Phenotypic molecular features of long-lived animal species. |
2023 |
Jove M; Mota-Martorell N; Fernandez-Bernal A; Portero-Otin M; Barja G; Pamplona R. |
Article d'investigació |
| Lipidomic alterations in the cerebral cortex and white matter in sporadic Alzheimer's disease. |
2023 |
Obis E; Sol J; Andres-Benito P; Martin-Gari M; Mota-Martorell N; Galo-Licona JD; Piñol-Ripoll G; Portero-Otin M; Ferrer I; Jove M; Pamplona R. |
Article d'investigació |
| Plasma acylcarnitines and aromatic amino acids as sex specific hub metabolites of the human aging metabolome. |
2023 |
Sol J; Obis E; Mota-Martorell N; Pradas I; Galo-Licona JD; Martin-Garí M; Fernández-Bernal A; Ortega-Bravo M; Mayneris-Perxachs J; Arnoriaga-Rodríguez M; Moreno-Navarrete JM; Ricart W; Biarnes C; Pedr |
Article d'investigació |
| Lipid adaptations against oxidative challenge in the healthy adult human brain. |
2023 |
Jove M; Mota-Martorell N; Obis E; Sol J; Martin-Gari M; Ferrer I; Portero-Otin M; Pamplona R |
Article d'investigació |
| Hakuna MAM-tata: Investigating the role of mitochondrial-associated membranes in ALS. |
2023 |
Fernandez-Bernal A; Mota-Martorell N; Pamplona R; Area-Gomez E; Portero-Otin M. |
Article d'investigació |
| mTOR Complex 1 Content and Regulation Is Adapted to Animal Longevity. |
2022 |
Mota Martorell, N.; Jové, M.; Pamplona, R. |
Review |
| Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals |
2022 |
Mota Martorell, N.; Jové, M.; Berdún, R.; Òbis, È.; Barja, G.; Pamplona, R. |
Article d'investigació |
| Selective brain regional changes in lipid profile with human aging. |
2022 |
Mota Martorell, N.; Andrés Benito, P.; Martín Gari, M.; Galo Licona, J.D.; Sol, J.; Fernández Bernal, A.; Portero Otín, M.; Ferrer, I.; Jove, M.; Pamplona, R. |
Article d'investigació |
| Long-lived Humans Have a Unique Plasma Sphingolipidome. |
2022 |
Pradas, I.; Jové, M.; Huynh, K.; Ingles, M.; Borras, C.; Mota Martorell, N.; Galo Licona, J.D.; Puig, J.; Viña, J.; Meikle, P.J.; Pamplona, R. |
Article d'investigació |
| ARID1A-deficient cells require HDAC6 for progression of endometrial carcinoma. |
2022 |
Megino Luque, C.; Sisó, P.; Mota Martorell, N.; Navaridas, R.; de la Rosa, I.; Urdanibia, I.; Albertí Valls, M.; Santacana, M.; Pinyol, M.; Bonifaci, N.; Macià, A.; Llobet Navas, D.; Gatius, S.; Matia |
Article d'investigació |
| Industrial by‐products as a novel circular source of biocompatible extracellular vesicles |
2021 |
Cristina Lorca; Moisés Laparra; María Virtudes Céspedes; Laura Casaní; Sergi Florit; Mariona Jové; Natàlia Mota‐Martorell; Elisabet Vilella; Xavier Gallart‐Palau; Aida Serra |
Article d'investigació |
| Methionine transsulfuration pathway is upregulated in long-lived humans. |
2021 |
Mota Martorell, N.; Jove, M.; Borras, C.; Berdun, R.; Obis, E.; Sol, J.; Cabre, R.; Pradas, I.; Galo Licona, J.D.; Puig, J.; Viña, J.; Pamplona, R. |
Article d'investigació |
| Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity? |
2021 |
Pamplona, R.; Jove, M.; Mota Martorell, N.; Barja, G. |
Article d'investigació |
| New insights into human prefrontal cortex aging with a lipidomics approach |
2021 |
Jové, M.; Mota Martorell, N.; Torres, P.; Portero Otin, M.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology |
2021 |
Jové, M.; Mota Martorell, N.; Torres, P.; Ayala, V.; Portero Otin, M.; Ferrer, I.; Pamplona, R. |
Review |
| Plasma methionine metabolic profile is associated with longevity in mammals |
2021 |
Mota Martorell, N.; Jové, M.; Berdún, R.; Pamplona, R. |
Article d'investigació |
| Up-Regulation of Specific Bioactive Lipids in Celiac Disease |
2021 |
Martín Masot, R.; Galo Licona, J.D.; Mota Martorell, N.; Sol, J.; Jové, M.; Maldonado, J.; Pamplona, R.; Nestares, T. |
Article d'investigació |
| Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age |
2021 |
Jové, M.; Cabré, R.; Mota Martorell, N.; Martin Garí, M.; Obis, È.; Ramos, P.; Canales, I.; Galo Licona, J.D.; Sol, J.; Nogueras, L.; Torres, P.; Portero Otín, M.; Ayala, V.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partially related to peroxisome impairment |
2020 |
Andres Benito, P.; Gelpi, E.; Jove, M.; Mota Martorell, N.; Obis, E.; Portero Otin, M.; Povedano, M.; Pujol, A.; Pamplona, R.; Ferrer, I. |
Article d'investigació |
| Alterations in one-carbon metabolism in celiac disease. |
2020 |
Martin-Masot, R.; Mota-Martorell, N.; Jove, M.; Maldonado, J.; Pamplona, R.; Nestares, T. |
Article d'investigació |
| Succination of protein thiols in human brain aging. |
2020 |
Jove, M.; Pradas, I.; Mota-Martorell, N.; Cabre, R.; Ayala, V.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian maximum longevity. |
2020 |
Mota-Martorell, N.; Jove, M.; Pradas, I.; Sanchez, I.; Gomez, J.; Naudi, A.; Barja, G.; Pamplona, R. |
Article d'investigació |
| The advanced lipoxidation end-product malondialdehyde-lysine in aging and longevity. |
2020 |
Jove, M.; Mota-Martorell, N.; Pradas, I.; Martin-Gari, M.; Ayala, V.; Pamplona, R. |
Review |
| Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity |
2020 |
Mota Martorell, N.; Jove, M.; Pradas, I.; Berdún, R.; Sanchez, I.; Naudi, A.; Gari, E.; Barja, G.; Pamplona, R. |
Article d'investigació |
| The lipidome fingerprint of longevity. |
2020 |
Jove, M.; Mota-Martorell, N.; Pradas, I.; Galo-Licona, J.D.; Martin-Gari, M.; Obis, E.; Sol, J.; Pamplona, R. |
Review |
| Effects of aging and methionine restriction on rat kidney metabolome. |
2019 |
Pradas I; Jove M; Cabre R; Ayala V; Mota-Martorell N; Pamplona R. |
Article d'investigació |
| Biosynthesis de novo of glycerophospholipids and longevity. |
2019 |
Mota-Martorell N; Pradas I; Jove M; Naudi A; Pamplona R. |
Article d'investigació |
| Lipid profile in human frontal cortex is sustained throughout healthy adult lifespan to decay at advanced ages |
2018 |
Cabré R; Naudí A; Dominguez-Gonzalez M; Jové M; Ayala V; Mota-Martorell N; Pradas I; Nogueras L; Rué M; Portero-Otín M; Ferrer I; Pamplona R |
Article d'investigació |
| Sixty years-old is the breakpoint of the human frontal cortex aging. |
2017 |
Cabré R; Naudí A; Dominguez-Gonzalez M; Ayala V; Jové M; Mota-Martorell N; Piñol-Ripoll G;Gil-Villar MP; Rué M; Portero-Otín M; Ferrer I; Pamplona R |
Article d'investigació |
| Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system |
2017 |
Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. |
Article d'investigació |
| Human Aging Is a Metabolome-related Matter of Gender |
2016 |
Jové M, Maté I, Naudí A, Mota-Martorell N, Portero-Otín M, De la Fuente M, Pamplona R. |
Article d'investigació |
| Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex |
2016 |
Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I; Pamplona R. |
Article d'investigació |
| Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autopha |
2016 |
Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G. |
Article d'investigació |
| Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction |
2015 |
Gomez, A; Gomez, J; Lopez Torres, M; Naudí, A; Mota-Martorell, N; Pamplona, R; Barja, G. |
Article d'investigació |
